Which medication is a second-generation antipsychotic?

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Dive into medical terminology with The Pitt Medical Terminology Test. Enhance your learning using flashcards and multiple choice questions. Prepare for your exam confidently with detailed hints and explanations.

Multiple Choice

Which medication is a second-generation antipsychotic?

Explanation:
Second-generation antipsychotics, also called atypical antipsychotics, are designed to treat psychotic symptoms with fewer movement-related side effects than older drugs. They typically block dopamine D2 receptors but also strongly antagonize serotonin 5-HT2A receptors, which helps improve a broader range of symptoms, including some negative symptoms, while reducing extrapyramidal symptoms. Olanzapine is a classic example of this class. It combines D2 and 5-HT2A receptor antagonism to manage psychosis with a lower risk of motor-side effects compared with older medications like haloperidol or chlorpromazine, though it carries metabolic side effects such as weight gain and glucose issues. Haloperidol and chlorpromazine are traditional, first-generation antipsychotics with stronger D2 blockade and higher EPS risk. Lithium is a mood stabilizer, not an antipsychotic. So olanzapine fits the description of a second-generation antipsychotic.

Second-generation antipsychotics, also called atypical antipsychotics, are designed to treat psychotic symptoms with fewer movement-related side effects than older drugs. They typically block dopamine D2 receptors but also strongly antagonize serotonin 5-HT2A receptors, which helps improve a broader range of symptoms, including some negative symptoms, while reducing extrapyramidal symptoms.

Olanzapine is a classic example of this class. It combines D2 and 5-HT2A receptor antagonism to manage psychosis with a lower risk of motor-side effects compared with older medications like haloperidol or chlorpromazine, though it carries metabolic side effects such as weight gain and glucose issues.

Haloperidol and chlorpromazine are traditional, first-generation antipsychotics with stronger D2 blockade and higher EPS risk. Lithium is a mood stabilizer, not an antipsychotic. So olanzapine fits the description of a second-generation antipsychotic.

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